I can't setup my site on zymic. How setup nuke on zymic. help me please.

Using PHP Nuke is a very stupid idea considering the much better systems out there. Have you considered PHP Fusion?
In terms of learning how to install it, you should upload all of your files via FTP to your web hosting account then use the installer. (Zymic has tutorials of using FTP if your lost - Use the search feature)

Jacob.